Endocrine Abstracts

We found that mast cells were present in pubertal mammary glands, and hypothesized that they participate in mammary morphogenesis and are sensitive to IGF1, which is essential for mammary development.As independently reported in another model of mast cell deficiency (Developmental Biology 2010 337 124), mast cell-deficient W/Wv mice had significantly less terminal end buds and ducts and smaller gland areas than controls at 3, 6, ...